Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.70 |
| ▸ | DRD2 | P14416 | 8/20 | 0.70 |
| ▸ | DRD4 | P21917 | 8/20 | 0.70 |
| ▸ | HTR2A | P28223 | 8/20 | 0.70 |
| ▸ | DRD3 | P35462 | 8/20 | 0.70 |
| ▸ | HTR2C | P28335 | 7/20 | 0.70 |
| ▸ | HTR7 | P34969 | 6/20 | 0.70 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HRH1 | P35367 | 2/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinuperone SCHEMBL678891 | 1.00 | HTR1A (0.70) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10834325 | 0.92 | DRD2 (0.67) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10832658 | 0.91 | HTR1A (0.57) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10833658 | 0.89 | HTR1A (0.55) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10834159 | 0.88 | DRD2 (0.74) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10833626 | 0.87 | HTR1A (0.53) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10833664 | 0.86 | DRD2 (0.61) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10833527 | 0.85 | HTR2A (0.52) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10833345 | 0.85 | DRD2 (0.59) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10787321 | 0.84 | DRD2 (0.69) | HTR1ADRD2DRD4HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025031979-A1 | USE OF RIMCAZOLE TO TREAT CANCER | KYREXA LTD (GB) | 2025-02-13 | — | — | WO | disclosed |