Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.70 |
| ▸ | DRD2 | P14416 | 8/20 | 0.70 |
| ▸ | DRD4 | P21917 | 8/20 | 0.70 |
| ▸ | HTR2A | P28223 | 8/20 | 0.70 |
| ▸ | DRD3 | P35462 | 8/20 | 0.70 |
| ▸ | HTR2C | P28335 | 7/20 | 0.70 |
| ▸ | HTR7 | P34969 | 6/20 | 0.70 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HRH1 | P35367 | 2/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinuperone SCHEMBL31395265 | 1.00 | HTR1A (0.70) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10834325 | 0.92 | DRD2 (0.67) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10832658 | 0.91 | HTR1A (0.57) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10833658 | 0.89 | HTR1A (0.55) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10834159 | 0.88 | DRD2 (0.74) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10833626 | 0.87 | HTR1A (0.53) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10833664 | 0.86 | DRD2 (0.61) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10833527 | 0.85 | HTR2A (0.52) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10833345 | 0.85 | DRD2 (0.59) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL10787321 | 0.84 | DRD2 (0.69) | HTR1ADRD2DRD4HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018015915-A1 | A PARENTERAL CONTROLLED RELEASE COMPOSITION OF AN ATYPICAL ANTIPSYCHOTIC AGENT | CADILA HEALTHCARE LIMITED (IN) | 2018-01-25 | — | — | WO | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| EP-1091759-B1 | COMPOSITION FOR THE INDUCTION OF APOPTOSIS IN TARGET CELLS | UNIV DUNDEE (GB) | 2012-10-24 | — | — | EP | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| US-4590273-A | NEUROLEPTIC HYPOTENSIVE AND ANTIARRHYTHMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-05-20 | — | — | US | claimed |
| US-12251380-B2 | Depot systems comprising cariprazine or salts thereof | MAPI PHARMA LTD. (IL) | 2025-03-18 | — | — | US | disclosed |
| EP-4493274-A1 | DEPOT SYSTEMS COMPRISING CARIPRAZINE OR SALTS THEREOF | Mapi Pharma Ltd. (IL) | 2025-01-22 | — | — | EP | disclosed |
| US-20240238280-A1 | DEPOT SYSTEMS COMPRISING CARIPRAZINE OR SALTS THEREOF | MAPI PHARMA LTD. (IL) | 2024-07-18 | — | — | US | disclosed |
| US-11931357-B2 | Depot systems comprising Cariprazine or salts thereof | MAPI PHARMA LTD. (IL) | 2024-03-19 | — | — | US | disclosed |
| US-20230293515-A1 | DEPOT SYSTEMS COMPRISING CARIPRAZINE OR SALTS THEREOF | MAPI PHARMA LTD. (IL) | 2023-09-21 | — | — | US | disclosed |
| WO-2023175598-A1 | DEPOT SYSTEMS COMPRISING CARIPRAZINE OR SALTS THEREOF | MAPI PHARMA LTD. (IL) | 2023-09-21 | — | — | WO | disclosed |
| US-5162341-A | Piperidine Derivatives | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| WO-1992018127-A1 | USE OF SIGMA RECEPTOR ANTAGONISTS TO ENHANCE THE EFFECTS OF ANTIPSYCHOTIC DRUGS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-10-29 | — | — | WO | disclosed |
| WO-1992014463-A1 | USE OF SIGMA RECEPTOR ANTAGONISTS FOR TREATMENT OF AMPHETAMINE ABUSE | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-09-03 | — | — | WO | disclosed |
| WO-1992014464-A1 | USE OF SIGMA RECEPTOR ANTAGONISTS FOR TREATMENT OF COCAINE ABUSE | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-09-03 | — | — | WO | disclosed |
| US-4590273-A | NEUROLEPTIC HYPOTENSIVE AND ANTIARRHYTHMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-05-20 | — | — | US | disclosed |
| EP-0047923-B1 | ISOQUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238280-A1 | DEPOT SYSTEMS COMPRISING CARIPRAZINE OR SALTS THEREOF | MC2R, CRHR1, MC5R | HTR1A 1273/4885DRD2 93/4885DRD4 183/4885 |
| US-12251380-B2 | Depot systems comprising cariprazine or salts thereof | MC2R, CRHR1, MC5R | HTR1A 1273/4885DRD2 93/4885DRD4 183/4885 |
| US-20230293515-A1 | DEPOT SYSTEMS COMPRISING CARIPRAZINE OR SALTS THEREOF | MC2R, MC5R, CRHR1 | HTR1A 1271/4885DRD2 95/4885DRD4 190/4885 |
| US-11931357-B2 | Depot systems comprising Cariprazine or salts thereof | MC2R, MC5R, CRHR1 | HTR1A 1271/4885DRD2 95/4885DRD4 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.