⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31136836 | 0.82 | — | — | |
| SCHEMBL3610632 | 0.80 | — | — | |
| SCHEMBL30943170 | 0.79 | — | — | |
| SCHEMBL758078 | 0.76 | — | — | |
| SCHEMBL31136658 | 0.72 | — | — | |
| SCHEMBL15213283 | 0.72 | — | — | |
| SCHEMBL12346180 | 0.71 | — | — | |
| SCHEMBL3330004 | 0.70 | MEN1 (0.31) | — | |
| SCHEMBL4745567 | 0.69 | POLB (0.31) | — | |
| SCHEMBL1809810 | 0.68 | L3MBTL1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119384414-A | Compound used as SMARCA2/4 inhibitor and application thereof | 甘李药业股份有限公司 | 2025-01-28 | — | — | CN | disclosed |