Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24821104 | 0.93 | TRIM24 (0.38) | SRD5A2TRIM24MCL1BAK1PPARG | |
| SCHEMBL31397254 | 0.90 | MCL1 (0.38) | SRD5A2TRIM24MCL1BAK1PPARG | |
| SCHEMBL24818101 | 0.90 | GRM5 (0.37) | SRD5A2TRIM24MCL1BAK1PPARG | |
| SCHEMBL24821102 | 0.88 | SRD5A2 (0.41) | SRD5A2TRIM24MCL1BAK1GRM5 | |
| SCHEMBL31397430 | 0.85 | FFAR1 (0.41) | SRD5A2PPARGGRM5FFAR1PKM | |
| SCHEMBL31397043 | 0.83 | TRIM24 (0.37) | SRD5A2TRIM24MCL1BAK1PPARG | |
| SCHEMBL30274180 | 0.83 | PKM (0.41) | SRD5A2TRIM24MCL1BAK1GRM5 | |
| SCHEMBL31397093 | 0.83 | MCHR1 (0.36) | SRD5A2GRM5FFAR1PKM | |
| SCHEMBL30273755 | 0.83 | HDAC6 (0.40) | SRD5A2TRIM24MCL1BAK1GRM5 | |
| SCHEMBL23540929 | 0.83 | DGAT1 (0.40) | PPARGGRM5FFAR4PKMPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240424111-A1 | Degrader Compounds and Uses Thereof | CALICO LIFE SCIENCES LLC (US) | 2024-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240424111-A1 | Degrader Compounds and Uses Thereof | PTPN1, PTPN2, PTPN5 | SRD5A2 2076/4885TRIM24 2371/4885MCL1 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.