Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31397356 | 0.90 | DDB1 (0.54) | DDB1CRBNMTOR | |
| SCHEMBL23541139 | 0.76 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL23842106 | 0.75 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL27023164 | 0.74 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL23842108 | 0.74 | DDB1 (0.72) | DDB1CRBN | |
| SCHEMBL26094177 | 0.74 | CRBN (0.72) | DDB1CRBN | |
| SCHEMBL30026841 | 0.73 | DDB1 (0.53) | DDB1CRBNPIK3CAMTORPRKDC | |
| SCHEMBL31397145 | 0.73 | DDB1 (0.50) | DDB1CRBN | |
| SCHEMBL23541177 | 0.73 | DDB1 (0.54) | DDB1CRBNMTORPRKDC | |
| SCHEMBL24818103 | 0.72 | CRBN (0.70) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240424111-A1 | Degrader Compounds and Uses Thereof | CALICO LIFE SCIENCES LLC (US) | 2024-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240424111-A1 | Degrader Compounds and Uses Thereof | PTPN1, PTPN2, PTPN5 | DDB1 2296/4885CRBN 161/4885PIK3CA 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.