Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.37 |
| ▸ | FABP7 | O15540 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17548182 | 0.82 | MAPK14 (0.39) | MAPK14PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL4574087 | 0.77 | MAPK14 (0.46) | MAPK14PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL22032867 | 0.76 | PIK3CA (0.39) | MAPK14PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29858668 | 0.76 | ATAD2 (0.47) | PIK3CAPIK3CDPIK3CBPIK3CGFABP7 | |
| SCHEMBL31398138 | 0.76 | MAOB (0.46) | PIK3CAPIK3CDPIK3CBPIK3CGFABP7 | |
| SCHEMBL27185954 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL30839799 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL15507834 | 0.72 | ALDH1A1 (0.54) | PIK3CAPIK3CDPIK3CBPIK3CGFABP7 | |
| SCHEMBL2724261 | 0.72 | IKBKE (0.42) | PIK3CAPIK3CDPIK3CBPIK3CGFABP7 | |
| SCHEMBL1570328 | 0.71 | FABP7 (0.45) | MAPK14PIK3CAPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024262911-A1 | NOVEL PYRAZOLO PYRIMIDINE-BASED COMPOUND AND USE THEREOF | 주식회사 에이조스바이오 | 2024-12-26 | — | — | WO | disclosed |