Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 5/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26868062 | 0.83 | L3MBTL1 (0.42) | MAPTL3MBTL1TDO2BRD4RAB9A | |
| SCHEMBL7472158 | 0.79 | TDO2 (0.59) | MAPTL3MBTL1TDO2BRD4RAB9A | |
| SCHEMBL19367737 | 0.78 | MAPT (0.45) | MAPTL3MBTL1TDO2BRD4RAB9A | |
| SCHEMBL14711436 | 0.76 | TDO2 (0.67) | MAPTTDO2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20505270 | 0.72 | CYP19A1 (0.54) | MAPTRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL27751423 | 0.71 | LMNA (0.49) | MAPTRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL22637149 | 0.70 | TDO2 (0.51) | MAPTL3MBTL1TDO2BRD4ALDH1A1 | |
| SCHEMBL1167672 | 0.69 | MEN1 (0.47) | MAPTL3MBTL1TDO2BRD4RAB9A | |
| SCHEMBL22637099 | 0.68 | BRD4 (0.40) | MAPTL3MBTL1TDO2BRD4RAB9A | |
| SCHEMBL12492122 | 0.68 | CYP3A4 (0.48) | MAPTL3MBTL1TDO2BRD4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371412-A | CYP11B2 inhibitor compound, pharmaceutical composition and application thereof | 长春金赛药业有限责任公司 | 2025-01-28 | — | — | CN | disclosed |