Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57063 | 0.96 | ALDH1A1 (0.46) | DAOSMN1; SMN2ALDH1A1MAPK1TSHR | |
| SCHEMBL29051656 | 0.86 | SMN1; SMN2 (0.44) | DAOSMN1; SMN2ALDH1A1MAPK1TSHR | |
| SCHEMBL3660464 | 0.83 | DAO (0.39) | DAOSMN1; SMN2ALDH1A1MAPK1TSHR | |
| SCHEMBL10385894 | 0.83 | DAO (0.49) | DAOSMN1; SMN2ALDH1A1MAPK1MEN1 | |
| SCHEMBL9564682 | 0.82 | HPGD (0.40) | DAOSMN1; SMN2ALDH1A1MAPK1TSHR | |
| SCHEMBL10383861 | 0.81 | HPGD (0.39) | DAOSMN1; SMN2ALDH1A1MAPK1TSHR | |
| SCHEMBL5367666 | 0.81 | DAO (0.39) | DAOSMN1; SMN2ALDH1A1MAPK1TSHR | |
| SCHEMBL28245381 | 0.80 | SMN1; SMN2 (0.37) | DAOSMN1; SMN2ALDH1A1MAPK1TSHR | |
| SCHEMBL1290533 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MAPK1TSHRKDM4E | |
| SCHEMBL7559724 | 0.78 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1MAPK1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119439618-A | Negative photosensitive resin composition, preparation method thereof and hardening film | 深圳市道尔顿电子材料股份有限公司 | 2025-02-14 | — | — | CN | disclosed |