SCHEMBL57063

SCHEMBL57063

Cc1csc(C(=O)C(C)(C)N2CCOCC2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MAPK1 P28482 2/20 0.46
TSHR P16473 1/20 0.46
DAO P14920 1/20 0.45
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
THRB P10828 1/20 0.39
RECQL P46063 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 2/20 0.36
HPGD P15428 2/20 0.35
HSP90AA1 P07900 1/20 0.35
HSP90AB1 P08238 1/20 0.35
MMP12 P39900 3/20 0.35
MAPT P10636 1/20 0.35
MMP2 P08253 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL31398487 0.96 DAO (0.45) ALDH1A1SMN1; SMN2MAPK1TSHRDAO
SCHEMBL29051656 0.87 SMN1; SMN2 (0.44) ALDH1A1SMN1; SMN2MAPK1TSHRDAO
SCHEMBL3660464 0.87 DAO (0.39) ALDH1A1SMN1; SMN2MAPK1TSHRDAO
SCHEMBL10385894 0.86 DAO (0.49) ALDH1A1SMN1; SMN2MAPK1DAOMEN1
SCHEMBL9564682 0.85 HPGD (0.40) ALDH1A1SMN1; SMN2MAPK1TSHRDAO
SCHEMBL5367666 0.84 DAO (0.39) ALDH1A1SMN1; SMN2MAPK1TSHRDAO
SCHEMBL10383861 0.84 HPGD (0.39) ALDH1A1SMN1; SMN2MAPK1TSHRDAO
SCHEMBL1290533 0.82 SMN1; SMN2 (0.43) ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E
SCHEMBL7559724 0.82 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E
SCHEMBL28245381 0.81 SMN1; SMN2 (0.37) ALDH1A1SMN1; SMN2MAPK1TSHRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5925 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080305-A Polyacrylonitrile microchannel preparation method 2026-05-26 CN claimed
EP-3685231-B1 3D PRINTING WITH POLYMERIC NANOGEL PARTICLES THE REGENTS OF THE UNIV OF COLORADO A BODY CORPORATE A COLORADO NON PROFIT (US) 2026-05-13 EP claimed
WO-2025235504-A1 COMPOSITIONS AND METHODS FOR TREATING DENTAL HYPERSENSITIVITY COLGATE-PALMOLIVE COMPANY (US) 2025-11-13 WO claimed
US-12377188-B2 Double-crosslinked fibrin gel, raw material composition and kit thereof, and application thereof ZHEJIANG UNIVERSITY (CN) 2025-08-05 US claimed
WO-2025108043-A1 LIGNIN-BASED ACRYLATE PREPOLYMER, COMPOSITE PREPOLYMER, ADHESIVE COMPOSITION, PREPARATION METHOD, AND USE 中国石油化工股份有限公司 2025-05-30 WO claimed
WO-2025092692-A1 INK COMPOSITION, INK, AND PREPARATION METHOD AND USE THEREFOR 长胜纺织科技发展(上海)有限公司 2025-05-08 WO claimed
CN-119747185-A Photo-curing organic silicon/SiO with micro/nano mastoid structure2Preparation method of super-hydrophobic coating 浙江理工大学 2025-04-04 CN claimed
US-20250108143-A1 DOUBLE-CROSSLINKED FIBRIN GEL, RAW MATERIAL COMPOSITION AND KIT THEREOF, AND APPLICATION THEREOF ZHEJIANG UNIVERSITY (CN) 2025-04-03 US claimed
CN-119708913-A Temperature-variable ink, preparation method thereof and printed matter 当纳利(广东)印务有限公司 2025-03-28 CN claimed
EP-3932671-B1 DUAL-CURING PHASE SEPARATION TYPE CONTINUOUS 3D PRINTING HIGH-PRECISION PHOTOSENSITIVE RESIN COMPOSITION SUZHOU POLLY NEW MAT TECH CO LTD (CN) 2025-03-19 EP claimed
EP-1770119-A1 Crosslinkabe elastomer compositions, process for preparation, and use thereof Lanxess Deutschland GmbH (DE) 2007-04-04 EP claimed
WO-2006046864-A1 PHOTOCURABLE RESIN COMPOSITION AND OPTICAL DISK ADHESIVE JSR CORPORATION (JP) 2006-05-04 WO claimed
EP-1000385-B1 METHOD AND SYSTEM FOR PRODUCING ACTIVATING LIGHT ABSORBING LENSES Q2100 INC (US) 2004-04-28 EP claimed
US-20030013780-A1 Polyolefin materials having enhanced surface durability and methods of making the same by exposure to radiation SOLVAY ENGINEERED POLYMERS, INC. 2003-01-16 US claimed
US-6488882-B2 CURING A BASE COMPONENT OF A THERMOPLASTIC POLYOLEFIN, A RADIATION-CROSSLINKABLE COMPONENT TO INCREASE THE SURFACE DURABILITY AND A PHOTOINITIATOR TO INITIATE THE CROSSLINKING; SURFACE TREATMENT; WEAR RESISTANCE SOLVAY ENGINEERED POLYMERS 2002-12-03 US claimed
US-20010020047-A1 Polyolefin materials having enhanced surface durability and methods of making the same by exposure to radiation SOLVAY ENGINEERED POLYMERS, INC. 2001-09-06 US claimed
EP-0921152-A2 Polyolefin materials having enhanced surface durability and methods of making the same by exposure to radiation Ciba SC Holding AG (CH) 1999-06-09 EP claimed
EP-0902327-A2 Radiation sensitive composition JSR Corporation (JP) 1999-03-17 EP claimed
US-5847015-A Pigment-dispersed radiation-sensitive composition for color filters JSR CORPORATION (JP) 1998-12-08 US claimed
EP-0645678-B1 Radiation-sensitive composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1998-03-04 EP claimed