Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31398683 | 0.81 | NPC1 (0.61) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL1854705 | 0.81 | MAPK1 (0.59) | MAPK1RAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6984008 | 0.80 | HCAR3 (0.68) | MAPK1RAB9ANPC1L3MBTL1KDM4E | |
| SCHEMBL23320436 | 0.80 | RAB9A (0.54) | MAPK1RAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL19151089 | 0.77 | MAPK1 (0.54) | MAPK1RAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL13623144 | 0.76 | HPGD (0.57) | RAB9ANPC1SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL14505713 | 0.76 | HCAR3 (0.72) | MAPK1RAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL23003014 | 0.76 | MAPK1 (0.53) | MAPK1L3MBTL1KDM4EHCAR3DEGS1 | |
| SCHEMBL13739418 | 0.76 | MAPK1 (0.61) | MAPK1RAB9ANPC1L3MBTL1KDM4E | |
| SCHEMBL2772417 | 0.75 | MAPK1 (0.51) | MAPK1L3MBTL1KDM4EHCAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025039979-A1 | PROTEIN ARGININE METHYLTRANSFERASE-5 INHIBITOR AND PHARMACEUTICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2025-02-27 | — | — | WO | disclosed |