Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL26611624 | 1.00 | MTNR1A (0.34) | MTNR1AMTNR1BALDH1A1SMN1; SMN2HTT | |
| SCHEMBL26611503 | 0.90 | MTNR1A (0.36) | MTNR1AMTNR1BALDH1A1SMN1; SMN2HTT | |
| Bromide SCHEMBL18555920 | 0.72 | ATM (0.43) | MTNR1AMTNR1BALDH1A1HTT | |
| SCHEMBL22355197 | 0.70 | ATM (0.44) | MTNR1AMTNR1BALDH1A1 | |
| Bromide SCHEMBL26128657 | 0.70 | HTT (0.43) | MTNR1AMTNR1BALDH1A1HTT | |
| SCHEMBL26611910 | 0.69 | CCR9 (0.31) | — | |
| SCHEMBL26415684 | 0.69 | HTT (0.41) | MTNR1AMTNR1BALDH1A1HTT | |
| SCHEMBL30619161 | 0.64 | ALDH1A1 (0.36) | ALDH1A1 | |
| Bromide SCHEMBL7301343 | 0.64 | MAPT (0.41) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL26611886 | 0.64 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301134-A | Silicon fluoride heteroaromatic systems for theranostics and methods therefor | 富齐奥奈尔治疗诊断股份有限公司 | 2025-01-10 | — | — | CN | disclosed |