Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 7/20 | 0.63 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.63 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.63 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.63 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.63 |
| ▸ | PRKX | P51817 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | PRKACA | P17612 | 3/20 | 0.56 |
| ▸ | PRKACG | P22612 | 3/20 | 0.56 |
| ▸ | PRKACB | P22694 | 3/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.56 |
| ▸ | PRKCG | P05129 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908180 | 0.81 | ROCK2 (0.67) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL2907389 | 0.81 | ROCK2 (0.67) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL5650140 | 0.81 | KMT2A (0.77) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL31033068 | 0.81 | KMT2A (0.77) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL13513878 | 0.81 | ROCK2 (0.77) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL31399766 | 0.81 | ROCK2 (0.63) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL18138090 | 0.80 | KMT2A (0.75) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL19856464 | 0.80 | KMT2A (0.75) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| SCHEMBL31399751 | 0.78 | ROCK2 (0.59) | ROCK2ROCK1PRKCEPRKCDPRKD1 | |
| Hydroxyfasudil SCHEMBL1827528 | 0.77 | ROCK2 (0.75) | ROCK2ROCK1PRKCEPRKCDPRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739672-A1 | NEW COMPOUNDS | Aston University (GB) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008626-A1 | NEW COMPOUNDS | ASTON UNIVERSITY (GB) | 2025-01-09 | — | — | WO | disclosed |