Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31399736 | 0.88 | TGM2 (0.49) | TGM2SIGMAR1MAPK8FNTAFNTB | |
| SCHEMBL31399709 | 0.87 | TGM2 (0.54) | TGM2SIGMAR1MAPK8FNTAFNTB | |
| SCHEMBL31399739 | 0.86 | TGM2 (0.46) | TGM2SIGMAR1MAPK8FNTAFNTB | |
| SCHEMBL31399728 | 0.85 | MAPK8 (0.50) | TGM2SIGMAR1MAPK8FNTAFNTB | |
| SCHEMBL31399737 | 0.84 | TGM2 (0.49) | TGM2SIGMAR1MAPK8FNTAFNTB | |
| SCHEMBL17076468 | 0.81 | TGM2 (0.72) | TGM2SIGMAR1FNTAFNTBALDH1A1 | |
| SCHEMBL4194658 | 0.79 | ROCK2 (0.59) | TGM2SMN1; SMN2KDM4EHTTMEN1 | |
| SCHEMBL31261865 | 0.78 | SIGMAR1 (0.48) | TGM2SIGMAR1MAPK8FNTAFNTB | |
| SCHEMBL31399729 | 0.73 | TGM2 (0.46) | TGM2ALDH1A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL31399716 | 0.72 | CHRM1 (0.54) | TGM2ALDH1A1TSHRSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739672-A1 | NEW COMPOUNDS | Aston University (GB) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008626-A1 | NEW COMPOUNDS | ASTON UNIVERSITY (GB) | 2025-01-09 | — | — | WO | disclosed |