Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059940 | 0.76 | KDM4E (0.50) | SMN1; SMN2HPGDKDM4ECASP3ALDH1A1 | |
| SCHEMBL31261863 | 0.75 | HTT (0.42) | SMN1; SMN2HTTMITFS1PR4LMNA | |
| SCHEMBL31399752 | 0.74 | APEX1 (0.44) | APEX1SMN1; SMN2HTTMITFS1PR4 | |
| SCHEMBL31399756 | 0.74 | APEX1 (0.44) | APEX1SMN1; SMN2HTTMITFS1PR4 | |
| SCHEMBL1379068 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2HTTMITFS1PR4LMNA | |
| SCHEMBL5177349 | 0.72 | LOXL2 (0.43) | SMN1; SMN2KDM4EALDH1A1HTR1AADRA1D | |
| SCHEMBL22303101 | 0.72 | RXFP1 (0.52) | SMN1; SMN2HTTLMNAHPGDNPSR1 | |
| SCHEMBL20571815 | 0.71 | POLB (0.47) | APEX1SMN1; SMN2HTTLMNAKDM4E | |
| SCHEMBL28101227 | 0.70 | MAPT (0.59) | SMN1; SMN2HTTMITFS1PR4LMNA | |
| SCHEMBL19692833 | 0.70 | HTT (0.52) | SMN1; SMN2HTTMITFS1PR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739672-A1 | NEW COMPOUNDS | Aston University (GB) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008626-A1 | NEW COMPOUNDS | ASTON UNIVERSITY (GB) | 2025-01-09 | — | — | WO | disclosed |