Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.52 |
| ▸ | PRNP | P04156 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084106 | 0.80 | NPC1 (0.50) | KMT2APOLBCYP1A2ALDH1A1HPGD | |
| SCHEMBL22493827 | 0.77 | NUDT1 (0.47) | RXFP1PRNPKMT2APOLBGSTP1 | |
| SCHEMBL4059940 | 0.77 | KDM4E (0.50) | CYP1A2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL2116085 | 0.77 | CYP1A2 (0.54) | RXFP1KMT2APOLBCYP1A2ALDH1A1 | |
| SCHEMBL9379792 | 0.77 | MAPT (0.47) | RXFP1PRNPKMT2APOLBCYP1A2 | |
| SCHEMBL22440531 | 0.76 | KMT2A (0.42) | RXFP1PRNPKMT2APOLBCYP1A2 | |
| SCHEMBL21855732 | 0.76 | GSTP1 (0.43) | RXFP1PRNPKMT2APOLBALDH1A1 | |
| SCHEMBL29506065 | 0.76 | GSTP1 (0.43) | RXFP1PRNPKMT2APOLBALDH1A1 | |
| SCHEMBL8084767 | 0.76 | RAB9A (0.50) | KMT2APOLBALDH1A1MAPK1HPGD | |
| SCHEMBL14641227 | 0.76 | HTR1A (0.46) | RXFP1PRNPKMT2APOLBSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739672-A1 | NEW COMPOUNDS | Aston University (GB) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008626-A1 | NEW COMPOUNDS | ASTON UNIVERSITY (GB) | 2025-01-09 | — | — | WO | disclosed |
| WO-2020156243-A1 | SHP2 INHIBITOR AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2020-08-06 | — | — | WO | disclosed |