Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SI | P14410 | 3/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.39 |
| ▸ | NQO2 | P16083 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423180 | 1.00 | TDP1 (0.52) | TDP1MAPTRAB9AMAPK1L3MBTL1 | |
| SCHEMBL14764520 | 0.88 | MAPT (0.44) | TDP1MAPTRAB9AMAPK1L3MBTL1 | |
| SCHEMBL14764415 | 0.88 | MAPT (0.44) | TDP1MAPTRAB9AMAPK1L3MBTL1 | |
| SCHEMBL31643056 | 0.84 | RAB9A (0.53) | MAPTRAB9AMAPK1ALDH1A1GAA | |
| SCHEMBL20475325 | 0.84 | RAB9A (0.53) | MAPTRAB9AMAPK1ALDH1A1GAA | |
| SCHEMBL14842553 | 0.80 | KDM4E (0.62) | TDP1MAPTRAB9AMAPK1L3MBTL1 | |
| SCHEMBL183009 | 0.77 | NQO2 (0.57) | MAPTRAB9AMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL8604288 | 0.77 | MAPT (0.52) | MAPTRAB9AMAPK1ALDH1A1GAA | |
| SCHEMBL7527351 | 0.77 | TDP1 (0.56) | TDP1MAPTRAB9AMAPK1ALDH1A1 | |
| SCHEMBL23886102 | 0.76 | DRD4 (0.46) | MAPTRAB9AMAPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021868-A1 | TRAF2 INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2025-01-30 | — | — | WO | disclosed |