Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31399943 | 0.87 | KDM4E (0.33) | HSD17B10KDM4EKMT2AMEN1USP2 | |
| SCHEMBL31400029 | 0.85 | LMNA (0.36) | HSD17B10KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL31400002 | 0.84 | HSD17B10 (0.39) | HSD17B10KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL31399954 | 0.79 | HSD17B10 (0.39) | HSD17B10KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL31399923 | 0.74 | HTT (0.32) | HSD17B10KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL31399916 | 0.74 | HTT (0.32) | HSD17B10KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL31399921 | 0.72 | HTT (0.43) | HSD17B10KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL31400041 | 0.71 | HSD17B10 (0.35) | HSD17B10KDM4EKMT2AMEN1USP2 | |
| SCHEMBL31399972 | 0.70 | HSD17B10 (0.47) | HSD17B10KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL31399926 | 0.66 | HSD17B10 (0.64) | HSD17B10KDM4EKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021868-A1 | TRAF2 INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2025-01-30 | — | — | WO | disclosed |