Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 14/20 | 0.36 |
| ▸ | PIP4K2C | Q8TBX8 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31399954 | 0.94 | HSD17B10 (0.39) | HSD17B10KDM4ETSHRHTTPIP4K2C | |
| SCHEMBL31399921 | 0.89 | HTT (0.43) | HSD17B10KDM4ETSHRHTTPIP4K2C | |
| SCHEMBL31400041 | 0.86 | HSD17B10 (0.35) | HSD17B10KDM4ETSHRHTTPIP4K2C | |
| SCHEMBL31399982 | 0.84 | HSD17B10 (0.36) | HSD17B10KDM4EALDH1A1MEN1HPGD | |
| SCHEMBL31399945 | 0.84 | HSD17B10 (0.54) | HSD17B10KDM4ETSHRHTTPIP4K2C | |
| SCHEMBL31400029 | 0.78 | LMNA (0.36) | HSD17B10KDM4ETSHRHTTPIP4K2C | |
| SCHEMBL31399943 | 0.72 | KDM4E (0.33) | HSD17B10KDM4EALDH1A1MEN1HPGD | |
| SCHEMBL16018117 | 0.72 | ALDH1A1 (0.46) | HSD17B10KDM4EHTTPIP4K2CALDH1A1 | |
| SCHEMBL31399964 | 0.70 | TSHR (0.56) | HSD17B10TSHRHTTPIP4K2CALDH1A1 | |
| SCHEMBL31399926 | 0.70 | HSD17B10 (0.64) | HSD17B10KDM4EHTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021868-A1 | TRAF2 INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2025-01-30 | — | — | WO | disclosed |