Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 12/20 | 0.36 |
| ▸ | PIP4K2C | Q8TBX8 | 9/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31399921 | 0.88 | HTT (0.43) | LMNAKMT2AALDH1A1HSD17B10TSHR | |
| SCHEMBL31399982 | 0.85 | HSD17B10 (0.36) | LMNAKMT2AALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL31399923 | 0.85 | HTT (0.32) | LMNAKMT2AALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL31399916 | 0.85 | HTT (0.32) | LMNAKMT2AALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL31399972 | 0.84 | HSD17B10 (0.47) | LMNAKMT2AALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL31400002 | 0.78 | HSD17B10 (0.39) | LMNAKMT2AALDH1A1HSD17B10TSHR | |
| SCHEMBL31399943 | 0.73 | KDM4E (0.33) | KMT2AALDH1A1HSD17B10MEN1L3MBTL1 | |
| SCHEMBL31399954 | 0.72 | HSD17B10 (0.39) | LMNAKMT2AALDH1A1HSD17B10TSHR | |
| SCHEMBL31399964 | 0.70 | TSHR (0.56) | LMNAKMT2AALDH1A1HSD17B10TSHR | |
| SCHEMBL4597345 | 0.65 | KMT2A (0.80) | LMNAKMT2AALDH1A1CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021868-A1 | TRAF2 INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2025-01-30 | — | — | WO | disclosed |