SCHEMBL31401745

SCHEMBL31401745

Cc1ccc(Nc2ccccc2C(N)=O)c(F)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP2K2 P36507 6/20 0.66
MAP2K1 Q02750 6/20 0.66
CSF1R P07333 1/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
KDM4E B2RXH2 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
POLB P06746 1/20 0.49
KMT2A Q03164 1/20 0.49
MAPK8 P45983 1/20 0.48
MAPK10 P53779 1/20 0.48
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.48
SIRT2 Q8IXJ6 3/20 0.48
JAK2 O60674 1/20 0.47
JAK1 P23458 1/20 0.47
TYK2 P29597 1/20 0.47
STAT3 P40763 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30172477 0.82 MAP2K1 (0.63) MAP2K2MAP2K1MAPTHTT
SCHEMBL4748692 0.82 MAP2K1 (0.63) MAP2K2MAP2K1MAPTHTT
SCHEMBL5624281 0.80 MAP2K1 (1.00) MAP2K2MAP2K1
SCHEMBL24196074 0.79 MAP2K1 (0.58) MAP2K2MAP2K1CSF1R
SCHEMBL10424663 0.79 SIRT2 (0.62) KDM4EMAPTSIRT2CLCN2SIRT1
SCHEMBL18599172 0.77 MAP2K1 (0.71) MAP2K2MAP2K1CSF1R
SCHEMBL24074083 0.77 MAP2K1 (0.56) MAP2K2MAP2K1CSF1RKDM4EMEN1
SCHEMBL23398091 0.77 LMNA (0.53) MAP2K2MAP2K1KDM4ESMN1; SMN2MEN1
SCHEMBL3610761 0.76 MAPT (0.56) MAP2K2MAP2K1RAB9AKDM4ESMN1; SMN2
SCHEMBL11602443 0.76 FABP4 (0.66) KDM4EMEN1LMNAKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025007811-A1 AROMATIC AMIDE DERIVATIVE AND USE THEREOF 成都华健未来科技有限公司 2025-01-09 WO disclosed