Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14194018 | 0.77 | ALDH1A1 (0.36) | HDAC1HDAC6TSHR | |
| SCHEMBL20670577 | 0.76 | CES2 (0.47) | HDAC1HDAC6ALOX5APFEN1TSHR | |
| SCHEMBL20670887 | 0.76 | KDM4E (0.47) | HDAC1HDAC6ALOX5APFEN1TSHR | |
| SCHEMBL29664155 | 0.76 | CES2 (0.47) | HDAC1HDAC6ALOX5APFEN1TSHR | |
| SCHEMBL18097685 | 0.75 | MAOB (0.42) | — | |
| SCHEMBL5032374 | 0.75 | CES2 (0.38) | TSHR | |
| SCHEMBL20670574 | 0.73 | CYP3A4 (0.40) | HDAC1HDAC6ALOX5APFEN1 | |
| SCHEMBL4605786 | 0.73 | HDAC1 (0.36) | HDAC1HDAC6ALOX5APFEN1TSHR | |
| SCHEMBL30838209 | 0.73 | CYP3A4 (0.40) | HDAC1HDAC6ALOX5APFEN1 | |
| SCHEMBL4092168 | 0.73 | DGAT1 (0.43) | HDAC1HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038420-A1 | KAPPA OPIOID RECEPTOR ANTAGONIST AND METHODS AND PRODUCTS RELATED THERETO | Neumora Therapeutics, Inc. (US) | 2025-02-20 | — | — | WO | disclosed |