Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 11/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31402252 | 1.00 | EP300 (0.41) | EP300TDP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL31402264 | 1.00 | EP300 (0.41) | EP300TDP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL31402325 | 0.99 | TDP1 (0.40) | EP300TDP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL31402230 | 0.95 | TDP1 (0.36) | EP300TDP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL1862488 | 0.89 | ALDH1A1 (0.35) | TDP1KDM4ECYP1A2CYP2D6ALOX15 | |
| SCHEMBL11120553 | 0.83 | KDM4E (0.43) | EP300TDP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL1860579 | 0.80 | ALDH1A1 (0.40) | TDP1KDM4EHDAC6ALDH1A1 | |
| SCHEMBL25261116 | 0.79 | SCN9A (0.40) | TDP1KDM4EHDAC8HDAC3HDAC1 | |
| SCHEMBL2818119 | 0.79 | TDP1 (0.42) | EP300TDP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL10784428 | 0.78 | TDP1 (0.53) | EP300TDP1KDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074891-A1 | BIFUNCTIONAL SULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074891-A1 | BIFUNCTIONAL SULPHONAMIDE COMPOUNDS | MLKL, RIPK3, CASP9 | EP300 4588/4885TDP1 454/4885KDM4E 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.