Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086562 | 0.87 | LSS (0.45) | LSSKMT2ABCHECARM1PRMT6 | |
| SCHEMBL3135799 | 0.82 | LSS (0.41) | LSSKMT2ABCHECARM1PRMT6 | |
| SCHEMBL3140377 | 0.81 | LSS (0.47) | LSSKMT2AALDH1A1 | |
| SCHEMBL4086461 | 0.79 | ADRB2 (0.41) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4086563 | 0.78 | DPP4 (0.51) | LSS | |
| SCHEMBL3140933 | 0.77 | POLB (0.41) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL28757734 | 0.76 | CACNA1B (0.50) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3133481 | 0.74 | ADRB2 (0.39) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL3131545 | 0.71 | CCR5 (0.41) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3135805 | 0.71 | DPP4 (0.53) | LSSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636224-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE | PROSIDION LTD (GB) | 2010-07-14 | — | — | EP | disclosed |