Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.58 |
| ▸ | TDO2 | P48775 | 1/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140440 | 1.00 | CA1 (0.58) | CA1CA2NFKB1CA4TDO2 | |
| SCHEMBL3149846 | 0.87 | MIF (0.59) | CA1CA2NFKB1CA4TDO2 | |
| SCHEMBL3149835 | 0.87 | MIF (0.59) | CA1CA2NFKB1CA4TDO2 | |
| SCHEMBL1404884 | 0.83 | MAPT (0.59) | ARKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL1404883 | 0.83 | MAPT (0.59) | ARKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL344639 | 0.82 | ALDH1A1 (0.64) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL65191 | 0.82 | TDO2 (0.58) | CA1CA2NFKB1CA4TDO2 | |
| SCHEMBL14086377 | 0.82 | TDO2 (0.58) | CA1CA2NFKB1CA4TDO2 | |
| SCHEMBL344638 | 0.82 | ALDH1A1 (0.64) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL65190 | 0.82 | TDO2 (0.58) | CA1CA2NFKB1CA4TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105979942-B | For treatment or lenitive sulfamate derivatives | 比皮艾思药物研发有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-105979942-A | Sulfamate derivative compounds for use in treating or alleviating pain | 比皮艾思药物研发有限公司 | 2016-09-28 | — | — | CN | disclosed |
| US-20100081692-A1 | Novel 1-Benzyl-4-Piperidinamines that are Useful in the Treatment of COPD and Asthma | ASTRAZENECA AB (SE) | 2010-04-01 | — | — | US | disclosed |
| EP-1945613-A1 | NOVEL 1 -BENZYL-4-PIPERIDINAMINES THAT ARE USEFUL IN THE TREATMENT OF COPD AND ASTHMA | AstraZeneca AB (SE) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007053082-A1 | NOVEL 1 -BENZYL-4-PIPERIDINAMINES THAT ARE USEFUL IN THE TREATMENT OF COPD AND ASTHMA | ASTRAZENECA AB (SE) | 2007-05-10 | — | — | WO | disclosed |
| EP-0185319-B1 | FLUORO COUMARINS AS ANTILYMPHOEDEMA AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-09-06 | — | — | EP | disclosed |
| US-4749798-A | ANTIINFLAMMATORY, ANTISWELLING | BOEHRINGER BIOCHEMIA ROBIN SPA (IT) | 1988-06-07 | — | — | US | disclosed |
| EP-0185319-A2 | Fluoro coumarins as antilymphoedema agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1986-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081692-A1 | Novel 1-Benzyl-4-Piperidinamines that are Useful in the Treatment of COPD and Asthma | CCR1, CCR4, CCR10 | CA1 4317/4885CA2 2091/4885NFKB1 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.