SCHEMBL3140456

SCHEMBL3140456

CCCCCCCCNC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.51
GNAO1 P09471 2/20 0.51
GNAI1 P63096 2/20 0.51
SLC2A1 P11166 1/20 0.48
GBA1 P04062 6/20 0.44
S1PR4 O95977 2/20 0.44
S1PR1 P21453 2/20 0.44
S1PR3 Q99500 2/20 0.44
KDM4E B2RXH2 2/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
ALDH1A1 P00352 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
S1PR5 Q9H228 1/20 0.39
RECQL P46063 1/20 0.37
FUCA1 P04066 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17409734 1.00 GNAI3 (0.51) GNAI3GNAO1GNAI1SLC2A1GBA1
SCHEMBL990185 1.00 GNAI3 (0.51) GNAI3GNAO1GNAI1SLC2A1GBA1
SCHEMBL10633005 1.00 GNAI3 (0.51) GNAI3GNAO1GNAI1SLC2A1GBA1
SCHEMBL892676 1.00 GNAI3 (0.51) GNAI3GNAO1GNAI1SLC2A1GBA1
SCHEMBL11026100 1.00 GNAI3 (0.51) GNAI3GNAO1GNAI1SLC2A1GBA1
SCHEMBL11212575 1.00 GNAI3 (0.51) GNAI3GNAO1GNAI1SLC2A1GBA1
Ammonia Solution, Strong SCHEMBL7733882 0.98 GNAI3 (0.50) GNAI3GNAO1GNAI1SLC2A1GBA1
SCHEMBL5250714 0.98 GNAI3 (0.49) GNAI3GNAO1GNAI1SLC2A1GBA1
SCHEMBL3675581 0.96 SLC2A1 (0.48) GNAI3GNAO1GNAI1SLC2A1GBA1
1,2-Dibromoethane SCHEMBL27826246 0.93 GNAI3 (0.46) GNAI3GNAO1GNAI1SLC2A1GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0172413-B1 PROCESS FOR PRODUCING PIPERIDINE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-16 EP claimed
EP-0172413-A2 Process for producing piperidine derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-02-26 EP claimed
US-4144224-A FOR POLYOLEFINS, POLYAMIDES, AND POLYURETHANES CIBA-GEIGY CORPORATION (US) 1979-03-13 US claimed
JP-56062839-A None JP disclosed
JP-56062840-A None JP disclosed
JP-56062837-A None JP disclosed
JP-56062838-A None JP disclosed
JP-56062836-A None JP disclosed
JP-56062835-A None JP disclosed
EP-3048096-B1 SYNTHESIS OF TRIACETONE DIAMINE COMPOUNDS BY MEANS OF REDUCTIVE AMINATION BASED ON TRIACETONE DIAMINE AND ITS DERIVATIVES EVONIK DEGUSSA GMBH (DE) 2019-04-24 EP disclosed
US-10227300-B2 Synthesis of triacetonediamine compounds by reductive amination proceeding from triacetonediamine and derivatives thereof EVONIK DEGUSSA GMBH (DE) 2019-03-12 US disclosed
JP-S5662840-A METHOD FOR IMPROVING WEATHERING RESISTANCE OF POLYOLEFIN SUMITOMO CHEM CO LTD 1981-05-29 JP disclosed
JP-S5662837-A STABILIZATION TREATMENT OF POLYOLEFIN AGAINST PHOTODETERIORATION SUMITOMO CHEM CO LTD 1981-05-29 JP disclosed
JP-S5662838-A METHOD FOR IMPROVING WEATHERING RESISTANCE OF POLYOLEFIN SUMITOMO CHEM CO LTD 1981-05-29 JP disclosed
JP-S5662839-A TREATMENT FOR IMPROVING WEATHERING RESISTANCE OF POLYOLEFIN SUMITOMO CHEM CO LTD 1981-05-29 JP disclosed
US-4263202-A PHOTOSTABILIZERS FOR PLASTICS USING METAL PHENOLATES CIBA-GEIGY CORPORATION (US) 1981-04-21 US disclosed
US-4166813-A Polyalkylated 4-aminopiperidine derivatives SANKYO COMPANY LTD. (JP) 1979-09-04 US disclosed
US-4144224-A FOR POLYOLEFINS, POLYAMIDES, AND POLYURETHANES CIBA-GEIGY CORPORATION (US) 1979-03-13 US disclosed
EP-0000700-A1 Metal complexes with a chelating anion comprising a phenolate group, their preparation and their use as light stabilizers, especially for polymeric substances CIBA-GEIGY AG (CH) 1979-02-21 EP disclosed
US-4086204-A LIGHT STABILIZERS CHIMOSA CHIMICA ORGANICA S.P.A. (IT) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10227300-B2 Synthesis of triacetonediamine compounds by reductive amination proceeding from triacetonediamine and derivatives thereof PNMT, HNMT, TYR GNAI3 3898/4885GNAO1 3222/4885GNAI1 3981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.