Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22632451 | 0.82 | THRA (0.64) | THRATHRBL3MBTL1KMT2AATM | |
| SCHEMBL23663470 | 0.79 | THRB (0.60) | THRATHRBALDH1A1LMNAL3MBTL1 | |
| SCHEMBL29632829 | 0.78 | THRB (0.61) | THRATHRB | |
| SCHEMBL29527864 | 0.77 | THRB (0.56) | THRATHRB | |
| SCHEMBL31405659 | 0.76 | THRA (0.43) | THRATHRBCA12CA1CA9 | |
| SCHEMBL22632759 | 0.75 | THRA (0.92) | THRATHRB | |
| SCHEMBL23663170 | 0.75 | THRB (0.65) | THRATHRBLMNAL3MBTL1 | |
| SCHEMBL22632721 | 0.75 | THRB (0.60) | THRATHRB | |
| SCHEMBL29632804 | 0.74 | THRB (0.63) | THRATHRB | |
| SCHEMBL29522950 | 0.73 | THRB (0.48) | THRATHRBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024260309-A1 | THR-β RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE METHOD THEREFOR | 西威埃医药技术（上海）有限公司 | 2024-12-26 | — | — | WO | disclosed |