Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD4 | P01730 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MMP15 | P51511 | 1/20 | 0.35 |
| ▸ | MMP16 | P51512 | 1/20 | 0.35 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31405676 | 0.87 | THRB (0.34) | CD4HTR6ARMCL1 | |
| SCHEMBL31405693 | 0.86 | ALK (0.41) | HTR6ALKCYP19A1L3MBTL1KLK7 | |
| SCHEMBL31405734 | 0.86 | HTR6 (0.35) | HTR6ALKCYP19A1L3MBTL1KLK7 | |
| SCHEMBL29414674 | 0.85 | CD4 (0.42) | CD4HTR6ALKCYP19A1AR | |
| SCHEMBL22632610 | 0.85 | CD4 (0.42) | CD4HTR6ALKCYP19A1AR | |
| SCHEMBL29414672 | 0.85 | CD4 (0.42) | CD4HTR6ALKCYP19A1AR | |
| SCHEMBL22632484 | 0.84 | ALK (0.37) | HTR6ALKCYP19A1L3MBTL1KLK7 | |
| SCHEMBL38660565 | 0.84 | ALK (0.37) | HTR6ALKCYP19A1L3MBTL1KLK7 | |
| SCHEMBL22632786 | 0.83 | CD4 (0.42) | CD4HTR6ALKCYP19A1AR | |
| SCHEMBL31258414 | 0.83 | CD4 (0.42) | CD4HTR6ALKCYP19A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024260309-A1 | THR-β RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE METHOD THEREFOR | 西威埃医药技术（上海）有限公司 | 2024-12-26 | — | — | WO | disclosed |