Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 6/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660565 | 0.90 | ALK (0.37) | ALKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22632484 | 0.90 | ALK (0.37) | ALKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22632487 | 0.90 | ALK (0.38) | ALKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31405692 | 0.86 | CD4 (0.42) | ALKHTR6CYP19A1KLK7KDM4E | |
| SCHEMBL31405734 | 0.85 | HTR6 (0.35) | ALKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22632787 | 0.84 | PDE4A (0.34) | ALKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29414832 | 0.84 | PDE4A (0.34) | ALKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22632905 | 0.82 | ALK (0.40) | ALKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22632471 | 0.81 | HTR6 (0.34) | ALKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22632472 | 0.80 | THRA (0.35) | ALKPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024260309-A1 | THR-β RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE METHOD THEREFOR | 西威埃医药技术（上海）有限公司 | 2024-12-26 | — | — | WO | disclosed |