⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31406977 | 0.93 | — | — | |
| SCHEMBL31406978 | 0.86 | — | — | |
| SCHEMBL21837311 | 0.82 | — | — | |
| SCHEMBL31678879 | 0.79 | — | — | |
| SCHEMBL17453456 | 0.69 | RPS6KB1 (0.31) | — | |
| SCHEMBL31406975 | 0.69 | TGFBR1 (0.32) | — | |
| SCHEMBL31406971 | 0.69 | AURKA (0.32) | — | |
| SCHEMBL21837302 | 0.68 | GPR119 (0.31) | — | |
| SCHEMBL31406979 | 0.67 | HIF1A (0.37) | — | |
| SCHEMBL17453474 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270229-A1 | THIENO[3,2-d]PYRIMIDINE, FURO[3,2-d]PYRIMIDINE, AND PYRROLO[3,2-D]PYRIMIDINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2025-08-28 | — | — | US | disclosed |
| US-20250042913-A1 | THIENO[3,2-d]PYRIMIDINE, FURO[3,2-d]PYRIMIDINE, AND PYRROLO[3,2-D]PYRIMIDINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2025-02-06 | — | — | US | disclosed |