Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | AOC1 | P19801 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9949489 | 0.85 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3POLBMEN1 | |
| SCHEMBL10175184 | 0.79 | CA12 (0.46) | SLC6A2SLC6A4MEN1CYP1A2CYP3A4 | |
| SCHEMBL5878684 | 0.77 | SLC6A4 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2KDM4C | |
| SCHEMBL29829964 | 0.77 | CYP11B1 (0.49) | SLC6A2SLC6A4SLC6A3POLBMEN1 | |
| SCHEMBL7330298 | 0.77 | CA12 (0.41) | SLC6A2SLC6A4SLC6A3AOC1AOC3 | |
| SCHEMBL5114144 | 0.77 | CYP11B1 (0.49) | SLC6A2SLC6A4SLC6A3POLBMEN1 | |
| SCHEMBL4893069 | 0.77 | AOC1 (0.53) | AOC1AOC3CYP1A2CYP2C19CYP2A6 | |
| SCHEMBL9662870 | 0.77 | CA12 (0.41) | SLC6A2SLC6A4SLC6A3AOC1AOC3 | |
| SCHEMBL7672393 | 0.77 | CA12 (0.44) | SLC6A2SLC6A4SLC6A3POLBKDM4C | |
| SCHEMBL24316214 | 0.76 | TSHR (0.48) | MEN1GAATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743455-A1 | SARM1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012296-A1 | SARM1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-16 | — | — | WO | disclosed |