Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 9/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | AKT2 | P31751 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | PRKX | P51817 | 2/20 | 0.46 |
| ▸ | NEK4 | P51957 | 2/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.46 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.46 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.46 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.46 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | SGK2 | Q9HBY8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646089 | 0.86 | AAK1 (0.44) | AAK1CYP17A1CTSSCTSKALDH1A1 | |
| SCHEMBL127326 | 0.85 | RIPK1 (0.60) | RIPK1CTSSCTSK | |
| SCHEMBL2481921 | 0.85 | RIPK1 (0.60) | RIPK1CTSSCTSK | |
| SCHEMBL3349953 | 0.85 | RIPK1 (0.60) | RIPK1CTSSCTSK | |
| SCHEMBL3372679 | 0.85 | AAK1 (0.43) | AAK1CYP17A1CTSSCTSKALDH1A1 | |
| SCHEMBL31407217 | 0.85 | AAK1 (0.46) | AAK1CYP17A1CTSSCTSKALDH1A1 | |
| SCHEMBL28995700 | 0.84 | PPARG (0.45) | RIPK1CTSSCTSKALDH1A1 | |
| SCHEMBL2011973 | 0.84 | CTSS (0.47) | RIPK1CTSSCTSK | |
| SCHEMBL1553363 | 0.84 | CTSS (0.47) | RIPK1CTSSCTSK | |
| SCHEMBL17619268 | 0.84 | PPARG (0.45) | RIPK1CTSSCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743455-A1 | SARM1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012296-A1 | SARM1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-16 | — | — | WO | disclosed |