SCHEMBL127326

SCHEMBL127326

CC(C)(C)OC(=O)N[C@@H](CO)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.60
CTSK P43235 4/20 0.56
CTSS P25774 3/20 0.56
GPR88 Q9GZN0 3/20 0.50
MAPT P10636 1/20 0.49
ATM Q13315 1/20 0.49
CTSL P07711 1/20 0.47
CTSB P07858 1/20 0.47
GABRB1 P18505 1/20 0.46
GABRB2 P47870 1/20 0.46
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3349953 1.00 RIPK1 (0.60) RIPK1CTSKCTSSGPR88MAPT
SCHEMBL2481921 1.00 RIPK1 (0.60) RIPK1CTSKCTSSGPR88MAPT
SCHEMBL2701580 0.94 RIPK1 (0.55) RIPK1CTSKCTSSGPR88MAPT
SCHEMBL14831426 0.91 CTSK (0.52) RIPK1CTSKCTSSGPR88ATM
SCHEMBL14831425 0.91 CTSK (0.52) RIPK1CTSKCTSSGPR88ATM
SCHEMBL21349963 0.89 GPR88 (0.53) RIPK1CTSKCTSSGPR88
SCHEMBL56698 0.88 CTSK (0.53) RIPK1CTSKCTSSMAPTATM
SCHEMBL4353938 0.88 CTSK (0.53) RIPK1CTSKCTSSMAPTATM
SCHEMBL56596 0.88 CTSK (0.53) RIPK1CTSKCTSSMAPTATM
SCHEMBL5020954 0.88 CTSK (0.52) RIPK1CTSKCTSSMAPTCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025019172-A1 ANTIMICROBIAL EXTRACTANT FORMED FROM COPPER-CONTAINING SOURCE CORNING INCORPORATED (US) 2025-01-23 WO claimed
CN-104560461-A Washing agent for mercury-polluted building wastes YANTAI SHUNLONG CHEMICAL TECHNOLOGY CO LTD 2015-04-29 CN claimed
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS INC (US) 2026-01-01 US disclosed
US-12377100-B2 Toll like receptor modulator compounds GILEAD SCIENCES, INC. (US) 2025-08-05 US disclosed
EP-4551563-A2 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2025-05-14 EP disclosed
US-20250145552-A1 PROCESS FOR REDUCTION OF CARBOXYLIC ACIDS WITH AMMONIA BORANE CATALYZED BY LEWIS ACID PURDUE RESEARCH FOUNDATION 2025-05-08 US disclosed
WO-2025064869-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER CIDARA THERAPEUTICS, INC. (US) 2025-03-27 WO disclosed
WO-2025019172-A1 ANTIMICROBIAL EXTRACTANT FORMED FROM COPPER-CONTAINING SOURCE CORNING INCORPORATED (US) 2025-01-23 WO disclosed
US-20240174662-A1 SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES CILAG AG (CH) 2024-05-30 US disclosed
US-11958844-B2 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and pharmaceutical composition comprising the same CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2024-04-16 US disclosed
WO-2024010810-A2 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2024-01-11 WO disclosed
EP-1156054-A1 DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2001-11-21 EP disclosed
US-5854268-A Azetidine, pyrrolidine and piperidine derivatives MERCK SHARP & DOHME, LTD. (GB) 1998-12-29 US disclosed
US-5280027-A Quinazoline containing compound IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-01-18 US disclosed
EP-0365045-B1 Perhydrothiazepine derivatives, their preparation and their therapeutic use SANKYO CO (JP) 1993-12-01 EP disclosed
EP-0459730-A2 Anti-tumour compounds ZENECA LIMITED (GB) 1991-12-04 EP disclosed
EP-0161801-B1 PERHYDROTHIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE SANKYO COMPANY LIMITED (JP) 1990-11-07 EP disclosed
EP-0365045-A1 Perhydrothiazepine derivatives, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1990-04-25 EP disclosed
US-4699905-A HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 1987-10-13 US disclosed
EP-0161801-A2 Perhydrothiazepine derivatives, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1985-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250145552-A1 PROCESS FOR REDUCTION OF CARBOXYLIC ACIDS WITH AMMONIA BORANE CATALYZED BY LEWIS ACID ADH1A, ADH1C, ADH5 RIPK1 3317/4885CTSK 2839/4885CTSS 2574/4885
US-11958844-B2 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and pharmaceutical composition comprising the same HDAC6, HDAC1, HDAC3 RIPK1 2705/4885CTSK 1624/4885CTSS 1909/4885
US-12377100-B2 Toll like receptor modulator compounds TLR8, TLR3, TLR6 RIPK1 255/4885CTSK 3582/4885CTSS 4368/4885
US-20240174662-A1 SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES SIK2, SIK1, SGK2 RIPK1 240/4885CTSK 1178/4885CTSS 4076/4885
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF FCGR2A, FCGR1A, FCGR3B RIPK1 3074/4885CTSK 2406/4885CTSS 1555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.