SCHEMBL31407237

SCHEMBL31407237

CNC(C)c1c(C)cncc1C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10073172 0.76
SCHEMBL2403041 0.75 CA1 (0.42) CYP3A4
SCHEMBL8285909 0.75 RAPGEF4 (0.40)
SCHEMBL23134995 0.75 RAPGEF4 (0.40)
SCHEMBL31407219 0.72 APLNR (0.33)
SCHEMBL24434881 0.72
SCHEMBL31407226 0.72
SCHEMBL31407277 0.72 CYP3A4 (0.38) CYP3A4CYP2C19
SCHEMBL28590932 0.69
SCHEMBL24850162 0.68 TRPA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743455-A1 SARM1 INHIBITORS F. Hoffmann-La Roche AG (CH) 2026-05-20 EP disclosed
WO-2025012296-A1 SARM1 INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2025-01-16 WO disclosed