Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 3/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408238 | 0.87 | SMN1; SMN2 (0.40) | PRKAG1PRKAA1PRKAB1SMN1; SMN2MAPT | |
| SCHEMBL31408403 | 0.86 | SMN1; SMN2 (0.37) | PRKAG1PRKAA1PRKAB1SMN1; SMN2MAPT | |
| SCHEMBL31408611 | 0.85 | SMN1; SMN2 (0.41) | PRKAG1PRKAA1PRKAB1SMN1; SMN2MAPT | |
| SCHEMBL31408586 | 0.84 | SMN1; SMN2 (0.40) | PRKAG1PRKAA1PRKAB1SMN1; SMN2MAPT | |
| SCHEMBL31408351 | 0.84 | SMN1; SMN2 (0.40) | PRKAG1PRKAA1PRKAB1SMN1; SMN2MAPT | |
| SCHEMBL31408354 | 0.84 | PRKAG1 (0.48) | PRKAG1PRKAA1PRKAB1SMN1; SMN2MTNR1A | |
| SCHEMBL31408372 | 0.83 | TDO2 (0.39) | PRKAG1PRKAA1PRKAB1SMN1; SMN2MAPT | |
| SCHEMBL31408506 | 0.83 | SMN1; SMN2 (0.39) | PRKAG1PRKAA1PRKAB1SMN1; SMN2MAPT | |
| SCHEMBL31408545 | 0.83 | PTGES (0.46) | PRKAG1PRKAA1PRKAB1SMN1; SMN2MTNR1A | |
| SCHEMBL31408452 | 0.81 | SMN1; SMN2 (0.44) | PRKAG1PRKAB1SMN1; SMN2MAPTMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |