Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408430 | 0.92 | MAPK1 (0.37) | MAPK1SMN1; SMN2MLLT1MEN1KMT2A | |
| SCHEMBL31408279 | 0.91 | SMN1; SMN2 (0.36) | MAPK1SMN1; SMN2MLLT1LRRK2ALDH1A1 | |
| SCHEMBL31408404 | 0.89 | LRRK2 (0.36) | MAPK1SMN1; SMN2MLLT1LRRK2 | |
| SCHEMBL31408509 | 0.88 | SMN1; SMN2 (0.34) | MAPK1SMN1; SMN2MLLT1 | |
| SCHEMBL31408514 | 0.87 | SMN1; SMN2 (0.36) | MAPK1SMN1; SMN2MLLT1MEN1MAPT | |
| SCHEMBL31408537 | 0.87 | SMN1; SMN2 (0.36) | MAPK1SMN1; SMN2MLLT1LRRK2MEN1 | |
| SCHEMBL31408376 | 0.87 | JAK2 (0.40) | MEN1KMT2A | |
| SCHEMBL31408237 | 0.86 | LRRK2 (0.35) | MAPK1SMN1; SMN2LRRK2 | |
| SCHEMBL31408429 | 0.86 | LRRK2 (0.35) | MAPK1SMN1; SMN2LRRK2 | |
| SCHEMBL31408327 | 0.86 | LRRK2 (0.35) | MAPK1SMN1; SMN2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |