Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 5/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408279 | 0.93 | SMN1; SMN2 (0.36) | MAPK1SMN1; SMN2MLLT1KITP2RY12 | |
| SCHEMBL31408356 | 0.92 | POLB (0.39) | MAPK1SMN1; SMN2MLLT1PDK1HPGD | |
| SCHEMBL31408537 | 0.90 | SMN1; SMN2 (0.36) | MAPK1SMN1; SMN2MLLT1KITALK | |
| SCHEMBL31408514 | 0.90 | SMN1; SMN2 (0.36) | MAPK1SMN1; SMN2MLLT1KITPTGES | |
| SCHEMBL31408376 | 0.89 | JAK2 (0.40) | ALKMEN1KMT2A | |
| SCHEMBL31408237 | 0.88 | LRRK2 (0.35) | MAPK1SMN1; SMN2CYP2C9CYP2C19EPHX2 | |
| SCHEMBL31408429 | 0.88 | LRRK2 (0.35) | MAPK1SMN1; SMN2CYP2C9CYP2C19EPHX2 | |
| SCHEMBL31408327 | 0.88 | LRRK2 (0.35) | MAPK1SMN1; SMN2CYP2C9CYP2C19EPHX2 | |
| SCHEMBL31408404 | 0.88 | LRRK2 (0.36) | MAPK1SMN1; SMN2MLLT1ALKPTGES | |
| SCHEMBL31408457 | 0.86 | SMN1; SMN2 (0.42) | MAPK1SMN1; SMN2PTGESMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |