Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408429 | 1.00 | LRRK2 (0.35) | LRRK2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL31408237 | 1.00 | LRRK2 (0.35) | LRRK2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL31408537 | 0.93 | SMN1; SMN2 (0.36) | LRRK2SMN1; SMN2PDCD1CD274MAPK1 | |
| SCHEMBL31408430 | 0.88 | MAPK1 (0.37) | SMN1; SMN2MAPK1CYP2C9CYP2C19EPHX2 | |
| SCHEMBL31408279 | 0.87 | SMN1; SMN2 (0.36) | LRRK2SMN1; SMN2MAPK1 | |
| SCHEMBL31408356 | 0.86 | POLB (0.39) | LRRK2SMN1; SMN2MAPK1 | |
| SCHEMBL31408437 | 0.85 | SMN1; SMN2 (0.34) | LRRK2SMN1; SMN2PDCD1CD274MAPK1 | |
| SCHEMBL31408514 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2PDCD1CD274MAPK1EPHX2 | |
| SCHEMBL31408404 | 0.84 | LRRK2 (0.36) | LRRK2SMN1; SMN2PDCD1CD274MAPK1 | |
| SCHEMBL31408376 | 0.83 | JAK2 (0.40) | CCNT1JAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |