Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | JUN | P05412 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408327 | 0.93 | LRRK2 (0.35) | SMN1; SMN2MAPK1LRRK2JAK2JAK3 | |
| SCHEMBL31408429 | 0.93 | LRRK2 (0.35) | SMN1; SMN2MAPK1LRRK2JAK2JAK3 | |
| SCHEMBL31408237 | 0.93 | LRRK2 (0.35) | SMN1; SMN2MAPK1LRRK2JAK2JAK3 | |
| SCHEMBL31408437 | 0.90 | SMN1; SMN2 (0.34) | SMN1; SMN2MAPK1PTGESLRRK2CHRNA7 | |
| SCHEMBL31408430 | 0.90 | MAPK1 (0.37) | SMN1; SMN2MAPK1PTGESALKMLLT1 | |
| SCHEMBL31408514 | 0.88 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPK1PTGESCHRNA7PDCD1 | |
| SCHEMBL31408279 | 0.88 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPK1PTGESLRRK2ALK | |
| SCHEMBL31408356 | 0.87 | POLB (0.39) | SMN1; SMN2MAPK1LRRK2MLLT1MEN1 | |
| SCHEMBL31408404 | 0.86 | LRRK2 (0.36) | SMN1; SMN2MAPK1PTGESLRRK2CHRNA7 | |
| SCHEMBL31408575 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2PTGESMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |