SCHEMBL31408656

SCHEMBL31408656

[O-][S+](c1cccc(F)c1)c1cccc(F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.42
NFE2L2 Q16236 3/20 0.41
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
PKM P14618 1/20 0.37
MAPK1 P28482 1/20 0.37
THPO P40225 1/20 0.37
NPC1 O15118 1/20 0.37
CHRM5 P08912 1/20 0.37
GRM5 P41594 1/20 0.37
RAB9A P51151 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
TAAR1 Q96RJ0 2/20 0.35
PARP1 P09874 1/20 0.35
ESR2 Q92731 1/20 0.35
IDO1 P14902 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776053 1.00 ACHE (0.42) ACHENFE2L2CES2CES1CYP1A2
SCHEMBL776449 0.93 NFE2L2 (0.42) ACHENFE2L2CES2CES1CYP1A2
SCHEMBL7938013 0.91 NFE2L2 (0.39) ACHENFE2L2CES2CES1CYP1A2
SCHEMBL7938438 0.82 ACHE (0.38) ACHENFE2L2CES2CES1TAAR1
SCHEMBL776964 0.81 ACHE (0.44) ACHENFE2L2CES2CES1CYP1A2
SCHEMBL18331412 0.81 ACHE (0.39) ACHENFE2L2CES2CES1CYP1A2
SCHEMBL20048774 0.81 ACHE (0.39) ACHENFE2L2CES2CES1CYP1A2
SCHEMBL4579747 0.79 ACHE (0.46) ACHENFE2L2CES2CES1CYP1A2
SCHEMBL18796114 0.78 CYP1A2 (0.41) ACHECYP1A2NPC1RAB9A
SCHEMBL24335595 0.78 ACHE (0.41) ACHENFE2L2CES2CES1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504523-A Preparation method of fluorine-containing phenyl sulfoxide compound 苏州源起材料科技有限公司 2025-02-25 CN disclosed