Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20488395 | 0.82 | RECQL (0.55) | HTTSMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL30665825 | 0.82 | RECQL (0.55) | HTTSMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL29948484 | 0.81 | MAPT (0.63) | WDR5HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL403355 | 0.81 | MAPT (0.63) | WDR5HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15031211 | 0.79 | KCNMA1 (0.66) | HTTSMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL3142244 | 0.79 | HDAC1 (0.55) | HTTSMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL14260294 | 0.78 | MEN1 (0.49) | HTTSMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL13414593 | 0.78 | WDR5 (0.56) | WDR5HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18146435 | 0.77 | KMT2A (0.60) | HTTSMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL3526801 | 0.77 | KMT2A (0.56) | WDR5HTTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466180-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-18 | — | — | US | disclosed |
| US-8466180-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-18 | — | — | US | disclosed |
| US-20100076078-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CORP PROTECTION, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| EP-2069287-A1 | INSECTICIDAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008031534-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008031534-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076078-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | WDR5 2245/4885HTT 2382/4885SMN1; SMN2 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.