⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389640 | 0.77 | RIPK1 (0.34) | — | |
| SCHEMBL25430904 | 0.76 | — | — | |
| SCHEMBL25431955 | 0.76 | — | — | |
| SCHEMBL24942446 | 0.76 | SLC6A2 (0.30) | — | |
| SCHEMBL31389630 | 0.74 | RIPK1 (0.39) | — | |
| SCHEMBL31389700 | 0.73 | — | — | |
| SCHEMBL31389490 | 0.73 | GRM5 (0.37) | — | |
| SCHEMBL31389725 | 0.72 | RIPK1 (0.37) | — | |
| SCHEMBL31409374 | 0.72 | PLAT (0.34) | — | |
| SCHEMBL14926120 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |