SCHEMBL31409463

SCHEMBL31409463

COC(=O)[C@@H](C)c1ccc(OC)c(OC)c1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.54
ALDH1A1 P00352 1/20 0.54
ACHE P22303 2/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
HPGD P15428 1/20 0.51
HIF1A Q16665 6/20 0.51
PTGS2 P35354 2/20 0.50
PTGS1 P23219 1/20 0.50
MT-CO2 P00403 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
KMT2A Q03164 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5022505 1.00 CYP2C19 (0.54) CYP2C19ALDH1A1ACHECA1CA2
SCHEMBL31409467 1.00 CYP2C19 (0.54) CYP2C19ALDH1A1ACHECA1CA2
SCHEMBL31083332 1.00 CYP2C19 (0.54) CYP2C19ALDH1A1ACHECA1CA2
SCHEMBL490875 0.86 TSHR (0.59) MT-CO2NPSR1
SCHEMBL16865531 0.86 MT-CO2 (0.55) ACHEPTGS2PTGS1MT-CO2KMT2A
SCHEMBL8193391 0.85 ACHE (0.54) CYP2C19ACHECA1CA2HPGD
SCHEMBL7241661 0.85 ALDH1A1 (0.51) ALDH1A1CA1CA2HIF1APTGS2
SCHEMBL2742620 0.85 ALDH1A1 (0.51) CYP2C19ALDH1A1HPGDPTGS2PTGS1
SCHEMBL3314391 0.85 MT-CO2 (0.50) ALDH1A1ACHECA1CA2PTGS2
SCHEMBL2067938 0.85 AKR1C3 (0.55) ALDH1A1PTGS2PTGS1MT-CO2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734977-A2 NOVEL TRPV1 AGONISTS AND USES THEREOF Neucures, Inc. (US) 2026-05-06 EP disclosed
WO-2025006675-A9 NOVEL TRPV1 AGONISTS AND USES THEREOF NEUCURES, INC. (US) 2025-03-13 WO disclosed
WO-2025006675-A2 NOVEL TRPV1 AGONISTS AND USES THEREOF NEUCURES, INC. (US) 2025-01-02 WO disclosed