Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | DHPS | P49366 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282876 | 0.86 | HDAC1 (0.49) | HDAC4HDAC1HDAC6ADAM17DHPS | |
| SCHEMBL21768036 | 0.86 | ERCC1 (0.47) | HDAC1ADAM17PRMT5WDR77MEN1 | |
| SCHEMBL31409566 | 0.86 | HDAC1 (0.49) | HDAC4HDAC1HDAC6ADAM17DHPS | |
| SCHEMBL31409506 | 0.84 | DHPS (0.51) | HDAC4HDAC1HDAC6CYP11B2DHPS | |
| SCHEMBL31409533 | 0.83 | ADAM17 (0.57) | ADAM17MEN1KMT2A | |
| SCHEMBL6765103 | 0.83 | MEN1 (0.46) | HDAC4HDAC1HDAC6DHPSMEN1 | |
| SCHEMBL31667471 | 0.81 | DHPS (0.46) | HDAC4HDAC1HDAC6DHPSMEN1 | |
| SCHEMBL31409517 | 0.80 | ESR1 (0.48) | ADAM17MEN1KMT2A | |
| SCHEMBL9141408 | 0.80 | ADAM17 (0.43) | CYP19A1HDAC4HDAC1HDAC6ADAM17 | |
| SCHEMBL31667333 | 0.78 | DHPS (0.46) | HDAC4HDAC1HDAC6DHPSMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006553-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2025-01-02 | — | — | WO | disclosed |