Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3232814 | 0.77 | SRC (0.42) | MEN1MAPTOPRD1OPRK1HTT | |
| SCHEMBL414096 | 0.74 | AURKA (0.34) | AURKAKCNN4KCNA3MEN1SLC22A1 | |
| SCHEMBL31409604 | 0.74 | LPL (0.31) | — | |
| SCHEMBL30632638 | 0.70 | GABRP (0.31) | — | |
| SCHEMBL25670764 | 0.70 | RXFP1 (0.39) | — | |
| SCHEMBL25296298 | 0.69 | AURKA (0.34) | AURKAKCNN4KCNA3MEN1SLC22A1 | |
| SCHEMBL875874 | 0.69 | AURKA (0.34) | AURKAKCNN4KCNA3MEN1SLC22A1 | |
| SCHEMBL30228734 | 0.69 | AURKA (0.34) | AURKAKCNN4KCNA3MEN1SLC22A1 | |
| SCHEMBL21820970 | 0.67 | CYP11B1 (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL30498385 | 0.67 | CYP17A1 (0.34) | LMNACYP17A1TSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |