SCHEMBL31409604

SCHEMBL31409604

CC1(C)OB(c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ccnc(Cl)c23)OC1(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31409646 0.74 AURKA (0.34)
SCHEMBL21820851 0.74 LPL (0.33) LPLLIPG
SCHEMBL21820999 0.72 LIPE (0.33) LPLLIPG
SCHEMBL21820843 0.72 LIPE (0.33) LPLLIPG
SCHEMBL31409565 0.70 USP30 (0.38)
SCHEMBL21821115 0.68 IRAK4 (0.32) LPLLIPG
SCHEMBL30387520 0.68 IRAK4 (0.32) LPLLIPG
SCHEMBL21821014 0.68 IRAK4 (0.32) LPLLIPG
SCHEMBL3050736 0.68 JAK2 (0.32) LPLLIPG
SCHEMBL9940458 0.67 LIPE (0.35) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026997-A1 SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS MERCK PATENT GMBH (DE) 2025-02-06 WO disclosed