Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 12/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409705 | 0.70 | DYRK1A (0.36) | DYRK1ACDK2GSK3B | |
| SCHEMBL1741221 | 0.65 | MET (0.51) | — | |
| SCHEMBL1741232 | 0.64 | MET (0.47) | — | |
| SCHEMBL31409711 | 0.63 | RAPGEF4 (0.56) | DHODH | |
| SCHEMBL16876371 | 0.62 | SYK (0.60) | SYK | |
| SCHEMBL31409700 | 0.62 | DYRK1A (0.34) | DYRK1AGSK3B | |
| SCHEMBL1981416 | 0.61 | HPGD (0.54) | EPHX2DHODH | |
| SCHEMBL3770143 | 0.61 | DHODH (0.53) | EPHX2DHODHCDK2 | |
| SCHEMBL15084530 | 0.60 | CDK5 (0.41) | DYRK1ACDK2GSK3B | |
| SCHEMBL1921455 | 0.59 | EPHX2 (0.56) | EPHX2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |