Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ROS1 | P08922 | 1/20 | 0.31 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409641 | 0.74 | S1PR1 (0.35) | DYRK1AGSK3BKCNH2SCN9ACLK1 | |
| SCHEMBL3192003 | 0.73 | LTA4H (0.41) | DYRK1APIM1PIM3 | |
| SCHEMBL31409643 | 0.73 | CYP1A2 (0.34) | DYRK1ASCN9AMAPTPIM1 | |
| SCHEMBL31409562 | 0.72 | BRD4 (0.35) | LMNAMAPTHTTBRD4 | |
| SCHEMBL31409572 | 0.72 | SCN9A (0.33) | GSK3BSCN9ALMNAMAPTHTT | |
| SCHEMBL31409647 | 0.72 | DGAT1 (0.37) | NPBWR1MCHR1BRD4 | |
| SCHEMBL31617408 | 0.71 | NPBWR1 (0.33) | KCNH2NPBWR1MCHR1HTR2ASLC6A4 | |
| SCHEMBL31617409 | 0.71 | NPBWR1 (0.33) | KCNH2NPBWR1MCHR1HTR2ASLC6A4 | |
| SCHEMBL15084530 | 0.71 | CDK5 (0.41) | DYRK1AGSK3BCLK1CDK5CDK5R1 | |
| SCHEMBL31409697 | 0.70 | SYK (0.38) | DYRK1AGSK3BCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |