Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31410565 | 0.98 | — | — | |
| SCHEMBL31410536 | 0.69 | GRIN2D (0.37) | HDAC8MEN1ALDH1A1LMNACYP2D6 | |
| SCHEMBL115643 | 0.69 | MAPT (0.33) | HDAC8MEN1ALDH1A1LMNACYP2D6 | |
| Hydrochloric Acid SCHEMBL31410625 | 0.67 | GRIN2D (0.36) | MEN1ALDH1A1LMNACYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL31560366 | 0.67 | GRIN2D (0.36) | MEN1ALDH1A1LMNACYP2D6MAPT | |
| SCHEMBL121142 | 0.64 | CYP3A4 (0.30) | MAPT | |
| SCHEMBL120155 | 0.64 | CYP19A1 (0.40) | — | |
| SCHEMBL2894741 | 0.63 | LMNA (0.39) | MEN1ALDH1A1LMNACYP2D6MAPT | |
| SCHEMBL24276895 | 0.63 | TSHR (0.38) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL11020140 | 0.61 | ADRA2B (0.43) | MEN1LMNACHRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076017-A1 | CARBAMATES FOR USE AS SARM1 INHIBITORS | GENENTECH, INC. (US) | 2025-04-10 | — | — | WO | disclosed |