Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1322736 | 0.86 | CHRM2 (0.46) | ADRA2BADRA2CCHRM2CHRM4CHRM5 | |
| Methyl Alcohol SCHEMBL9850585 | 0.79 | CHRM2 (0.46) | ADRA2BADRA2CCHRM2CHRM4CHRM5 | |
| SCHEMBL9792509 | 0.77 | NOTUM (0.39) | NOTUMSLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL9796965 | 0.76 | NOTUM (0.35) | ADRA2BADRA2CNOTUMSLC6A2SLC6A4 | |
| Butane SCHEMBL19809192 | 0.76 | CHRM2 (0.47) | ADRA2BADRA2CCHRM2CHRM4CHRM5 | |
| SCHEMBL11112975 | 0.76 | SLC6A2 (0.44) | ADRA2BADRA2CCHRM2CHRM4CHRM5 | |
| SCHEMBL2841570 | 0.74 | ALDH1A1 (0.42) | ADRA2BADRA2CCHRM2CHRM4CHRM5 | |
| SCHEMBL11641507 | 0.74 | TSHR (0.42) | ADRA2BADRA2CCHRM2CHRM4CHRM5 | |
| SCHEMBL11018982 | 0.74 | LDHA (0.43) | ADRA2BADRA2CCHRM2CHRM4CHRM5 | |
| 1,2,4-Triazole SCHEMBL28874144 | 0.74 | ADRA2B (0.38) | ADRA2BADRA2CCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149115-A2 | Derivatives of 2-(1-imidazolyl)-ethanol | BOEHRINGER INGELHEIM KG (DE) | 1985-07-24 | — | — | EP | disclosed |