Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 13/20 | 0.97 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPRF | P10586 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | PTPRE | P23469 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lodoxamide SCHEMBL119881 | 0.98 | GPR35 (1.00) | GPR35PTPRCPTPRFPTPN2PTPRB | |
| SCHEMBL11946654 | 0.93 | GPR35 (0.90) | GPR35PTPRCPTPRFPTPN2PTPRB | |
| Lodoxamide SCHEMBL10897004 | 0.92 | GPR35 (0.88) | GPR35PTPRCPTPRFPTPN2PTPRB | |
| SCHEMBL12803235 | 0.88 | GPR35 (0.80) | GPR35PTPRCPTPRFPTPN2PTPRB | |
| SCHEMBL28582660 | 0.87 | GPR35 (0.79) | GPR35PTPRCPTPRFPTPN2PTPRB | |
| Lodoxamide SCHEMBL11864397 | 0.87 | GPR35 (0.78) | GPR35PTPRCPTPN2PTPRBPTPRE | |
| Lodoxamide SCHEMBL24175 | 0.85 | GPR35 (0.76) | GPR35PIN1PTPN1PTPRA | |
| SCHEMBL17471520 | 0.80 | GPR35 (0.68) | GPR35PIN1 | |
| SCHEMBL29758005 | 0.80 | GPR35 (0.69) | GPR35LMNAMAPTTSHRHTT | |
| SCHEMBL11568751 | 0.80 | GPR35 (0.69) | GPR35LMNAMAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203192-A1 | WOUND CARE FORMULATION | Northern Health And Social Care Trust (GB) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009037500-A1 | WOUND CARE FORMULATION | NORTHERN HEALTH AND SOCIAL CARE TRUST (GB) | 2009-03-26 | — | — | WO | disclosed |